Discover the next generation of startups.

AbInitio Bio

YCombinator

The Intelligence layer for Drug Manufacturing

Abinitio Bio builds foundation models for biomanufacturing, validated against wet lab data. Our first model, Echo, predicts manufacturing outcomes more accurately than standard models, and any pharma or CDMO can adapt it to their own workflow instantly. By making process decisions that take 6-18 months today in hours, we help teams avoid the cost of delay on a single program.

Absurd

YCombinator

The Creative OS for AI video

Absurd makes AI brand and performance ads at scale. Our last video for Kalshi ("Election Day") did 1M+ views, and our videos average 400K+ organic views. Companies like Hims, Kalshi, Replit, and Brex use Absurd to create production-quality videos in 72 hours. Try it at absurd.com

Adialante

YCombinator

Cancer screening without barriers

We know how to improve cancer outcomes by 8x-10x: you catch it early. MRI is the most robust and powerful cancer-detection tool in the world, yet systems cost millions to purchase, take months to install, and require high levels of technical skill to operate. We've redesigned MRI from the ground up with new physics, algorithms, and hardware, all to bring cancer screening to the entire world. Our mobile MRI is an imaging clinic on wheels. No equipment to buy, no infrastructure needed. For a flat per-scan fee, any medical site can offer MRI cancer screening. Starting with prostate cancer. Then everything else.

Advanced Metal Research

YCombinator

Machine intelligence for American Welding

America does not just need more welders. It needs welding knowledge that can scale. The American Welding Society projects 320,500 new welding professionals will be needed by 2029, with about 80,000 jobs to be filled annually from 2025 to 2029. More than 157,000 current welding professionals are approaching retirement. Welders are only a small share of the skilled-trades workforce, but welding accounts for an outsized share of projected capability demand. The market calls it a labor shortage. AMR sees a learning bottleneck. We are building American-made robotic welding cells that combine computer vision to provide real-time seam tracking and post-weld inspection to turn welding from a scarce manual process into a closed-loop manufacturing system that learns from every weld as it happens.

Aemon

YCombinator

The Forward-Deployed AI Research Engineer

Aemon is the first autonomous research engineer that delivers state-of-the-art solutions to your engineering problems. It generates, tests, and evolves thousands of approaches at machine speed to discover optimal solutions beyond what human experts can find. Aemon already set a new world record on an NP-hard math optimization problem with <$10 of compute, beating the previous record set by Google DeepMind in 2025. Ray and Richard (twin brothers) dropped out of UWaterloo and UIUC to build Aemon. They published at top AI conferences like ICLR and EMNLP before turning 20.

AgentPhone

YCombinator

Phone Numbers for AI Agents

The $2T global telecom industry was built for humans. Agents can't act in the real world today because without a phone number, they lack identity. AgentPhone gives every AI agent its own phone number to reach people and businesses through messages and calls.

Agentic Fabriq

YCombinator

The control plane for AI agents.

Agentic Fabriq helps companies securely manage what AI agents can access and do across business tools, data, and teams. We give each agent an identity, scoped permissions, approval flows, and audit logs, so employees and customer-facing workflows can use agents without relying on shared API keys, overbroad service accounts, or one-off integrations.

AgileMD

YCombinator

Predictive analytics and clinical pathways for hospitals

At AgileMD, we are building the most advanced real-time predictive analytics and clinical algorithms platform for hospitals. Our cloud-based engine helps thousands of doctors and nurses around the country make medical decisions, so that every patient receives the highest quality and value of care based on the latest medical knowledge and data.

Agnost AI

YCombinator

Product analytics for teams building conversational agents

Agnost AI helps teams building chat and voice AI agents understand what users want, where they get stuck, and why they drop off. We read production AI conversations, cluster recurring intents, feature requests, frustration, and failure patterns, then open PRs against prompts, tools, and harnesses to improve the agent.