Founders Directory LogoFounders Directory

Discover the next generation of startups.

A curated directory of high-growth companies backed by the world's most prestigious venture capital firms.

909Companies

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Cofactor Genomics logo

Cofactor Genomics

YCombinator

Cofactor closes the precision medicine gap with predictive diagnostics

Cofactor uses RNA and Predictive Immune Modeling to build better biomarkers and improve patient outcomes. Led by Jarret Glasscock and a group of expert human genome scientists,Cofactor has built a new category of diagnostic technology powered by unique and powerful RNA data models built on terabytes of data. The team recently had their technology validation peer-reviewed by the organizations that set standards for diagnostic technology (CAP, AMP) and is publishing in the Journal of Molecular Diagnostics. In addition, the team made news when Cancer Physicians who sit on the committee for patient treatment guidelines (NCCN) presented a clinical study using Cofactor’s technology showing superiority in predicting the patients who will respond to immunotherapy. This initial application is an acute problem recognized widely in the rapidly developing immunotherapy industry and represents north of a billion dollar TAM. After a number of recent key milestones, the team is taking the technology more broadly to 50% of cancers diagnosed in the US. Current investors include Menlo Ventures, DCVC, and Ascension Ventures (this last investor representing the funding arm for 13 National U.S. Healthcare Systems).

St. Louis, MOY Combinator LogoSummer 2015ActiveMedical DevicesBiotechDiagnostics
Cofia logo

Cofia

YCombinator

AI automations that implement themselves

Cofia learns how your team runs internal operations and automates the highest-ROI workflows, automatically.

New York City, NYY Combinator LogoWinter 2026Active
Cognito logo

Cognito

YCombinator

Frictionless, modern identity verification that starts with just a…

Cognito is the highest converting ID verification system on the market. By starting with just a user's phone number, Cognito can verify their name, date of birth, address, phone, and Social Security Number. The strong link formed between a user and their phone number builds trust while reducing friction.

San FranciscoY Combinator LogoSummer 2014AcquiredFintechB2BIdentitySan Francisco
Cohesion logo

Cohesion

YCombinator

Agents that automate research for institutional investors

Cohesion is building AI agents for hedge funds. Our agents track earnings and non-traditional datasets like podcasts and X/twitter. Analysts spend hours a week manually tracking these data sources and still miss relevant investing signals. Now, our agents do it for them autonomously.

New York City, NYY Combinator LogoSpring 2026Active
Coinbase logo

Coinbase

YCombinator

Buy, sell, and manage cryptocurrencies.

Founded in June of 2012, Coinbase is a digital currency wallet and platform where merchants and consumers can transact with new digital currencies like bitcoin, ethereum, and litecoin. Our vision is to bring more innovation, efficiency, and equality of opportunity to the world by building an open financial system. Our first step on that journey is making digital currency accessible and approachable for everyone. Two principles guide our efforts. First, be the most trusted company in our domain. Second, create user-focused products that are easier and more intuitive to use.

Los Angeles, CAY Combinator LogoSummer 2012PublicCrypto / Web3Los Angeles
Complir logo

Complir

YCombinator

Vanta for physical products

AI-powered product compliance platform that makes it easy for retailers to launch and scale products across borders without drowning in regulatory work. Complir's AI agents handle the regulations and documentation across every market you sell in - and keep your entire catalogue audit-ready.

San FranciscoY Combinator LogoSpring 2026ActiveSan Francisco
ComplyDo logo

ComplyDo

YCombinator

Global Compliance for Enterprises

The most flexible enterprise compliance engine that makes GRC teams 10x more efficient. Already trusted by global leaders and the largest EU enterprises. What it does: - Extracts requirements from any file - Maps them to controls and policies - Shows gaps and monitors changes - Advises on maturity and next steps

Berlin, GermanyY Combinator LogoFall 2025ActiveB2BComplianceLegalTechCybersecurityAI
Compresr logo

Compresr

YCombinator

LLM context compression for better accuracy

Compresr provides an API that compresses LLM context without losing what matters. It’s a drop-in for agents and RAG that cuts token costs and improves accuracy.

San Francisco, CAY Combinator LogoWinter 2026Active
Compyle logo

Compyle

YCombinator

The coding agent that actually collaborates with you

Compyle is a less autonomous coding agent that asks before it acts. We're like Cursor or Claude Code - but you won't need to rewrite your codebase every time you use it for more than a small task. We built Compyle because we were frustrated with the direction other coding agents are headed. They're all racing to be more autonomous, running for hours without human input. This doesn't work for real production code. When agents run autonomously, they make countless small decisions that pile up in your codebase. Engineers lose ownership - they don't know what was implemented, can't effectively debug or maintain it, and struggle to build on top of it. The code becomes a black box, and they're forced to throw it away. Compyle keeps engineers in the driver's seat.

San FranciscoY Combinator LogoFall 2025ActiveArtificial IntelligenceDeveloper ToolsAISan Francisco
Condor Energy logo

Condor Energy

YCombinator

Software for enterprise energy procurement.

Condor helps large electricity consumers - C&I and data centers - cut electricity costs by helping the grid. We are former electricity traders and energy physicists. We build an AI-powered software that our clients use to optimize their energy procurement - making sure they always have access to cheap & reliable power.

Paris, FranceY Combinator LogoWinter 2026Active
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