Discover the next generation of startups.

Confluence Labs

YCombinator

AI models that learn from experience

While modern AI excels in any area you can collect a lot of data for, it struggles in areas where data is sparse or costly to attain. Designing new molecules, discovering new physics, and engineering new materials are all domains where collecting data is extremely costly. We dream of a world where AI accelerates research in all of these domains and creates a more abundant future for humanity, but the current technology is not there. That’s why we started Confluence Labs. We are building AI that can design highly effective experiments in data-sparse domains and learn maximally from the data it already has.

Congruent

YCombinator

AI native radars for self-driving cars

At Congruent, we build radars for end-to-end autonomous systems. The most advanced autonomous systems are trained as a single neural network from raw sensor data to navigation actions. For a sensor to be included in these pipelines sensor stacks requires two key properties: access to raw sensor data and a high-fidelity sensor simulator. Current automotive radars have neither, they output heavily processed point clouds and no raw radar simulator exists for driving scenes. Congruent solves both problems: a radar architecture that exposes raw data, paired with a world model based radar simulator. Radar is the only depth sensor at a price point that scales to every car on the road and works in all weather conditions. Congruent is building the radar compatible with the training architectures that will make mass-market vehicles autonomous.

Conifer

YCombinator

Local-first least cost routing system to reduce 80%+ token spend

Conifer is one app that connects you to every AI model (local and cloud) and automatically routes each request to the cheapest model that accomplishes your goal. Most requests run free on your own hardware, so teams cut their AI bill by ~80% while replacing a dozen provider contracts with one interface and one invoice. For sensitive material like financials or user data, a secure mode pins everything on-device with no external API calls.

Constellation Space

YCombinator

AI operating system for mega-scale satellite networks.

Constellation Space is building the autonomous infrastructure layer for the next generation of space networking. As satellite constellations rapidly scale from hundreds of nodes to tens of thousands, traditional ground-based orchestration fundamentally breaks down. ConstellationOS bridges this gap by providing zero-intervention network handoffs, predictive thermal load-balancing, and sub-second optical routing. Our founding team spent years building and operating satellite systems at SpaceX, Blue Origin, and NASA. We started Constellation to solve the problem we kept running into: reactive monitoring doesn't scale. We are building the sub-second routing protocols and hyperscale load-balancing infrastructure that will manage the future of off-world telecommunications and compute. hello@constellation-io.com

Context.dev

YCombinator

We give AI agents realtime web context.

Context.dev gives AI agents structured data from any website through a single API. We help developers build smarter agents & products that depend on accurate, fresh web data. If you need structured data from the internet, you need Context.dev Proud to power agentic products at Mintlify, Super, Vizzy, Klarna, and 280 other companies.

Control Seat

YCombinator

Control and Monitoring of Industrial Operations

Control Seat is an innovative startup in the tech space.

Convexia

YCombinator

The world's first AI-maximalist pharma company

An AI-maximalist pharma platform. We use agents to buy drugs, run clinical trials, and sell for a profit. 10x faster and 20x leaner than incumbents. Sourcing Agent: Mines public/private databases and unstructured global data to surface overlooked preclinical candidates. Scientific Agent: Runs comp bio models (ESM-3, RFdiffusion, Boltz-2, AlphaFold) to assess safety and efficacy in silico. Commercial Agent: Analyzes FDA incentives, pricing dynamics, TAM, competitive landscape, and payer alignment. Clinical Agent: Runs digital twin simulations, evaluates CRO/CMC risk, and builds trial plans to Phase 1. PoS Agent: Evaluates the most critical factors that impact the likelihood of clinical trial success. Built by 2 Stanford CS students who have built 3 startups together before.

Copperlane

YCombinator

Agentic Mortgage Origination

Copperlane helps mortgage lenders accelerate the loan process and reduce mistakes in an application. We use AI agents to understand an applicant's profile, verify their documents, and complete initial underwriting tasks.

Corelayer

YCombinator

AI on-call engineer for data-heavy, regulated industries

Corelayer is the AI-native platform for production software support, built for data-heavy, regulated industries like finance and healthcare. It continuously monitors alerts, logs, infrastructure, and underlying data for issues and uses agents to debug and suggest fixes. We're helping teams at companies ranging from growth-stage fintechs to S&P 500 financial institutions spend less time on support and more on high-leverage work.